Influence of extraction solvent on the biological properties of maritime pine bark (Pinus pinaster)

Maritime pine bark (Pinus pinaster Aiton subsp. atlantica) is rich in polyphenols with known bioactive properties which are beneficial for human health. However, biological activities of extracts depend on the type extracted and characteristics these extractives several factors such as solvents used. The influence extraction solvent composition consequently has been poorly described. Thus, this study (water, ethanol ethanol-water (50/50 v/v%)) antibacterial anticancer P. samples were evaluated. LC-DAD-MS profiling different was also carried out to their polyphenol composition. Results show that must be carefully chosen respect foreseeing use extracts, since ethanolic hydroethanolic displayed greatest activity whereas water showed increased properties.